What drug omeprazole?

What drug omeprazole?


Generic Name: Omeprazole Brand: Conprazole, Gastrofer, Inhipump, Lanacer, Lokev, Meisec, Omed, Omeprazole Otto, OMZ, Opm, Ozid Ozid / Ozid IV, Prilos, Promezol, Pumpitor / Pumpitor DI, Redusec, Rindopump, Rocer, Stomacer, Stomacer, Stomacer, Stomacer, Stomacer, Stomacer, Stomacer, Stomacer, Stomacer Ulpraz, Zepral, Zeprazol, Zolacap, Zollocid, Contral, Dudencer, Losec, Norsec, Omeprazole Indo Farma, Omeprazole OGB Soho, Omevell, Onic, Oprezol, Prohibit, Protop, Regasec, Socid, Stomacer 40, Tamezol, Omzrazol stomach-acid-stomach.


What drug is Omeprazole?

Omeprazole is a medicine to treat stomach and esophagus problems caused by stomach acid. The way it works is by lowering the levels of acid produced by the stomach. Omeprazole can also relieve symptoms of abdominal heat, difficulty swallowing, and a cough that never goes away. Another function is to help heal acid damage in the stomach and esophagus, help prevent gastric sores, and can also prevent esophageal cancer. Omeprazole belongs to the proton pump inhibitors (PPIs) class of drugs.

If you want to treat yourself with this drug, omeprazole products which are sold freely are usually used to treat heartburn, aka heartburn which recurs every 2 times or more within one week. Because it takes 1-4 days for this drug to take effect, omeprazole products cannot eliminate these symptoms directly.

For over-the-counter medicines, pay attention to the instructions on the label to make sure this is the right medicine for you. Check the ingredients of the drug on the label even though this is not the first time you are taking this drug, because the manufacturer might change or add some ingredients. Omeprazole products with different brands may contain different ingredients and are intended for different problems. Consuming the wrong product risks harming you.

The dose of omeprazole and the side effects of omeprazole will be explained further below.

What are the rules for taking Omeprazole?

Read the medication guide and the Patient Information Brochure provided by the pharmacy, if available, before you get this medicine and every time you buy it again. If you have questions, ask your doctor or pharmacist.

Take omeprazole by mouth according to doctor's instructions, usually once a day, before eating. If you buy it without a prescription, follow the instructions on the packaging label. Doses are always given based on your health condition and how you respond to therapy. The dosage for children is also based on age and weight. It is prohibited to increase the dose or consume this drug more often without your doctor's approval. If you have questions, ask your doctor or pharmacist.

Do not crush, break or chew this tablet. Swallow the tablet with a glass of water.

If needed, antacid can be taken together with this drug. If you also take sucralfate, take omeprazole at least 30 minutes before sucralfate.

Use this medicine regularly to get its benefits. So you don't forget, take this medicine at the same time every day. Continue to take this medication according to the length of time the medication was instructed even though you feel better. If you buy this medicine without a doctor's prescription, don't take it more than 14 days unless your doctor allows it.

Tell your doctor if your condition does not improve or actually worsens. If you treat yourself, tell your doctor if heartburn still lasts after 14 days or if you have to take this medicine more than once every 4 months. If you feel you have a serious medical problem, seek medical help immediately.

How is Omeprazole stored?

This drug is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Omeprazole for adults?

  • Omeprazole dose for duodenal ulcer: 20 mg orally once a day before meals. Most patients recover in 4-8 weeks.
  • Omeprazole dose for peptic ulcers: 40 mg orally once a day before meals for 4-8 weeks.
  • Omeprazole dose for erosive esophagitis: 20 mg orally once a day before meals. This dose can be increased to 40 mg per day based on the clinical response and tolerance of the patient. Research has been carried out for the treatment and therapy of erosive esophagitis for 12 months.
  • Omeprazole dose for Zollinger-Ellison Syndrome: Initial dose = 60 mg orally once a day. The dosage varies according to the patient's needs. Maintenance dose = dose up to 120 mg, 3 times a day. Daily doses of more than 80 mg must be divided.
  • Omeprazole dose for gastric acid reflux: Initial dose = 20 mg orally once a day before meals for 4-8 weeks. This dose can be increased to 40 mg per day if needed. Maintenance dose = long-term treatment with a dose of 10-20 mg per day may be needed for treatment of refractory diseases and so far considered safe.
  • Omeprazole dose for multiple endocrine adenomas: Initial dose = 60 mg orally once a day before meals. This dose can be changed based on the desired response and tolerance of the patient. Maintenance dose = dose up to 120 mg, 3 times a day. Daily doses greater than 80 mg must be divided.
  • Omeprazole dose for systemic mastocytosis: Initial dose = 60 mg orally once a day before meals. This dose can be changed based on the desired response and tolerance of the patient. Maintenance dose: dose up to 120 mg, 3 times a day. Daily doses greater than 80 mg must be divided.
  • Omeprazole dose to prevent heartburn: 20 mg orally once a day before meals, for 14 days.

What is the dose of Omeprazole for children?

Omeprazole dose for toddlers

For gastric acid reflux: 0.7 mg / kg / once-daily dose will reduce the percentage of gastric and esophageal pH to less than 4, and reduce the number of reflux episodes in 10 neonates (mean PMA: 36.1 weeks, (34 to 40 weeks)] in trials. A higher dose has also been reported, which is 1 to 1.5 mg / kg / day.

Omeprazole dose for children and adolescents 1 - 16 years sufferers of acid reflux, gastric ulcer, and esophagitis

  • Body weight 5-10 kg: 5 mg once a day
  • Weight 10-20 kg: 10 mg once a day
  • Weight> 20 kg: 20 mg once a day
  • Alternative doses: Children aged 1 - 16 years: 1 mg / kg / dose, once or twice per day

Additional therapeutic doses of duodenal injury associated with Helicobacter pylori (combined with antibiotic therapy such as clarithromycin or clarithromycin and amoxicillin) in children

  • Body weight 15-30 kg: 10 mg twice daily
  • Weight> 30 kg: 20 mg twice daily

Note : The safety and efficacy of omeprazole in patients less than one year old and in children other than for the treatment of gastric acid and erosive esophagitis have not been determined.

In what dosage is Omeprazole available?

  • Capsules: 10 mg; 20 mg; 40 mg
  • Liquid: 2.5 mg; 10 mg

Side effects

What side effects can be experienced due to Omeprazole?

Seek immediate medical attention if you experience an allergic reaction: hives; difficulty breathing; swelling on the face, lips, tongue, or throat.

Contact your doctor immediately if you experience serious side effects from omeprazole, such as:

  • Liquid or bloody diarrhea
  • Low magnesium levels (dizziness, confusion, rapid or irregular heartbeat, sudden muscle movements, nervous feelings, muscle cramps, muscle weakness, feeling of numbness, coughing or feeling of suffocation, convulsions)

Common side effects of omeprazole are:

  • Fever
  • Symptoms of flu, such as nasal congestion, sneezing, sore throat
  • Stomach ache, bowel movements
  • Nausea, vomiting, mild diarrhea; or
  • Headache

Not everyone experiences the following side effects. There may be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Prevention & Warnings

What should be known before using Omeprazole?

Before using certain drugs, consider the risks and benefits first. This is a decision that you and your doctor must make. For this drug, note the following:


Tell your doctor if you experience an unusual or allergic reaction to this or other medication. Also tell your doctor if you have other types of allergies, such as food, coloring, preservatives, or animal allergies. For non-prescription products, read the label on the packaging carefully.


Research conducted to date has not shown problems that can inhibit the effectiveness of omeprazole in children aged 1-16 years. However, the safety and efficacy of these drugs in children younger than one year have not been established.


Research conducted to date has not shown problems that can inhibit the effectiveness of omeprazole in elderly patients.

Is Omeprazole safe for pregnant and lactating women?

There is no adequate research on the risks of drug use in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. Omeprazole falls into the category C (possibly at risk) pregnancy risk according to the US Food and Drugs Administration (FDA).

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk
  • B = No risk in several studies
  • C = Maybe risky
  • D = There is positive evidence of risk
  • X = Contraindications
  • N = Unknown


What medicines might interact with Omeprazole?

Although some drugs may not be taken together at all, in other cases some drugs can also be used together although interactions may occur. In cases like this, the doctor may change the dose, or do other prevention things that are needed. Let your doctor know if you are taking other medicines both over the counter and from a prescription.

Taking this drug with the medicines below are not recommended. Your doctor may not prescribe this drug to you or it will replace some of the drugs that you are already taking.

  • Rilpivirine

Although not recommended, to take omeprazole with the drugs below, in some cases a combination of these two drugs may be needed. If so, your doctor may change the dose or determine how often you should take one of these drugs.

  • Atazanavir
  • Bendamustine
  • Bosutinib
  • Citalopram
  • Clopidogrel
  • Clorazepate
  • Clozapine
  • Dabrafenib
  • Dasatinib
  • Delavirdine
  • Erlotinib
  • Eslicarbazepine Acetate
  • Indinavir
  • Ketoconazole
  • Ledipasvir
  • Methotrexate
  • Mycophenolate Mofetil
  • Nelfinavir
  • Nilotinib
  • Pazopanib
  • Saquinavir
  • Tacrolimus
  • Topotecan
  • Vismodegib

The combination with the drugs below can increase the risk of side effects, but the use of these two drugs together may be needed for your treatment. If you are prescribed these two drugs together, your doctor may change the dose or determine how often you should take one of these drugs.

  • Armodafinil
  • Carbamazepine
  • Cilostazol
  • Cranberry
  • Digoxin
  • Disulfiram
  • Fluconazole
  • Ginkgo Biloba
  • Iron
  • Levothyroxine
  • Raltegravir
  • St. John's Wort
  • Tipranavir
  • Triazolam
  • Voriconazole
  • Warfarin

Can food or alcohol interact with Omeprazole?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Omeprazole?

Other health conditions that you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

  • Diarrhea
  • Hypomagnesemia (low magnesium in the blood), or its history
  • Osteoporosis (bone problems)
  • Seizures or having experienced seizures - Use with caution. This medicine can worsen your health condition
  • Liver disease - Use with caution. Side effects may increase because the disposal of drugs from the body will take place more slowly


What should I do in an emergency or overdose?

In cases of emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Symptoms of an overdose, including:

  • Confusion
  • Drowsiness
  • Blurred vision
  • Fast and fast heartbeat
  • Nausea
  • Gag
  • Sweating
  • Blushing (body feels hot)
  • Headache
  • Dry mouth

What should I do if I miss a dose?

If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose.


MIMS. Omeprazole. 2016. http://mims.com/Indonesia/Home/GatewaySubscription/?generic=Omeprazole Accessed December 12th, 2015

Reviewed date: May 29, 2017 | Last Edited: May 29, 2017

Editor'S Choice