What drug is Tramadol?

What drug is Tramadol?


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What is the drug used for tramadol?

Tramadol medicine is a drug used to help reduce moderate to severe pain. Tramadol is a drug that is similar to narcotic analgesics. It works in the brain to change how your body feels and responds to pain.

How to use the drug Tramadol?

Tramadol drug is a type of drug that is taken orally or by mouth according to doctor's instructions, usually every 4 to 6 hours as needed to reduce pain. You can take this medicine with or without food.

If you experience nausea, try taking this medicine with food. Ask your doctor or pharmacist about other ways to deal with nausea (for example lying down for 1-2 hours with the slightest possible head movement).

The dosage is determined based on your medical condition and response to treatment. To reduce the risk of side effects, your doctor may ask you to start treatment with a low dose and slowly increase the dose. Follow the doctor's instructions carefully.

The maximum recommended dose is 400 mg per day. If you are 75 years or older, the recommended dosage is 300 mg per day. Do not increase the dose, take the medicine more often, or take it longer than prescribed. Stop taking this medicine if a doctor has instructed it.

Pain relievers will work more optimally if used immediately when new signs of pain appear. If you wait until the pain is severe, the medicine might not work too well.

If you have prolonged pain (for example due to arthritis), your doctor may also ask you to take narcotics. Other non-narcotic painkillers (such as acetaminophen, ibuprofen) may also be prescribed together with this drug. Ask your doctor or pharmacist if you have questions about using tramadol with other drugs.

Tramadol is a drug that may cause an addiction reaction, especially if it has been used routinely for a long time or in high doses. In cases like this, symptoms of addiction (such as fatigue, runny eyes, runny nose, nausea, sweating, muscle aches) can appear if you suddenly stop using this drug. To prevent this, your doctor may reduce the dose slowly. Contact your doctor or pharmacist for more details, and report symptoms of addiction if you experience it.

If this tramadol drug is used for a long time, its effectiveness may decrease. Talk to your doctor if these drugs don't work anymore.

Along with its benefits, tramadol is a drug that may also be (though rarely) addictive. This risk will increase if you have abused alcohol or drugs in the past. Take this medicine as prescribed to prevent the risk of addiction. Tell your doctor if the pain persists or worsens.

How is Tramadol stored?

Tramadol medicine is the drug that is best stored at room temperature, away from direct light and a damp place. Do not store in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Tramadol for adults?

For the use of chronic pain that is mild to severe enough and does not require a rapid analgesic effect, you can use an initial dose of 25 mg every morning.

  • For the dose to be increased, use 25 mg in stages in divided doses every 3 days to reach 100 mg per day, in the form of a 25 mg dose taken 4 times a day.
  • Then the total daily dose can be increased to 50 mg according to tolerance every 3 days to reach 200 mg per day, in the form of a 50 mg dose taken 4 times per day.
  • Treatment: After titration, tramadol 50 mg to 100 mg can be given as needed for pain relief every 4-6 hours, do not exceed 400 mg per day

To deal with moderate to severe chronic pain in adults who need comprehensive treatment for their pain over a longer period

  • Initial dose: 100 mg once a day and gradually increase if necessary 100 mg every 5 days to relieve pain and depend on body tolerance.
  • Maximum dose: Extended-release tablets should not be given at doses exceeding 300 mg per day

For patients who need a rapid analgesic effect and for patients whose conditions are in dire need of this drug so they can ignore the risks that can arise from higher initial doses. Give in a dose of 50 mg to 100 mg can be given as needed to relieve pain every 4 to 6 hours, not to exceed 400 mg per day.

Patients who are not on treatment with immediate-release (IR) tramadol, can be given an initial dose of 100 mg once a day and added can need as much as 100 mg gradually every 5 days to relieve pain and adjusted to the needs and tolerance of patients. The maximum dose of 300 mg per day

Patients currently on immediate-release tramadol treatment (IR, taking into account the dose of IR tramadol in 24 hours, can be used with the initial dose rounded to the next lowest 100 mg increase. The dose may vary depending on the needs and tolerance of the patient. Maximum dose as much 300 mg per day, do not use more than this dose.

What is the dose of Tramadol for children?

1. Usage from 4 to 16 years of age:

  • Immediate release formulation: 1 to 2 mg / kg / dose every 4 to 6 hours
  • Maximum single dose: 100 mg
  • The maximum total daily dose is lower than: 8 mg / kg / day or 400 mg / day

2. For use 16 years and over:

  • Initial dose: 50 to 100 mg every 4 to 6 hours
  • Maximum dose: 400 mg / day

Alternatively, for patients who do not need a quick effect, the side effects of this drug can be reduced by starting the dose at 25 mg / day and increasing it by 25 mg every 3 days to a maximum of 25 mg 4 times a day.

The dose can then be increased by 50 mg every 3 days according to tolerance, up to 50 mg 4 times a day. The maximum dose usage is 400 mg in one day

In what dosages is Tramadol available?

Tramadol drug is a drug that is available in tablets of 100 mg, 200 mg and 300 mg.

Side effects

What tramadol effects might I get?

Seek immediate medical attention if you experience an allergic reaction due to the effects of tramadol such as itching, difficulty breathing, swelling of the face, lips, tongue, or throat. If you experience the effects of tramadol as follows, contact your doctor immediately:

  • agitation, hallucinations, fever, rapid heartbeat, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting
  • convulsions
  • a red, blistered skin rash
  • shallow breath, weak pulse.

Other side effects of tramadol that are not too serious include:

  • dizzy, like spinning the room
  • constipation, stomach churning
  • headache
  • sleepy
  • feeling nervous or anxious.

Not all people experience these side effects. There may be some tramadol effects not mentioned above. If you have concerns about the effects of certain tramadol, consult your doctor or pharmacist.

Prevention & Warnings

What should I know before taking Tramadol?

Before using certain drugs, consider the risks, benefits and side effects of tramadol first. This is a decision that you and your doctor must make. For this drug, note the following:

1. Allergy

Tell your doctor if you experience an unusual or allergic reaction to this or other medication. Also tell your doctor if you have other types of allergies, such as food, coloring, preservatives, or animal allergies. For non-prescription products, read the label on the packaging carefully.

2. Children

Adequate research has not been conducted on the relationship between age and the effects of Rybix ™ ODT, Ryzolt ™ and Ultram® tablets in children under 16 years. Safety and efficacy have not been determined.

3. Elderly

Adequate research to date has not shown a specific problem for elderly patients that requires restrictions on the use of tramadol in the elderly.

However, elderly patients are more likely to be affected by side effects (such as constipation, dizziness or fainting, abdominal pain, weak body) and some age-related problems such as liver, kidney, or heart problems, so special adjustments and attention may be needed regarding dosage for elderly patients who need tramadol.

Addiction as a dangerous effect of tramadol

Someone who is addicted to the drug tramadol is a person who will usually have a dangerous physical dependence. Addicts tend to continue taking these drugs to relieve aches and pains suffered.

The effects of tramadol in addition to being addictive, usually also will cause side effects such as nausea, vomiting, constipation, dizziness, drowsiness and headaches that can occur at any time while you are still taking these drugs. Then the most severe thing, addiction as a side effect of tramadol can cause death and decreased brain function.

Meanwhile, if an addict begins to stop taking it, his body will cause a symptom of tramadol withdrawal. Symptoms of tramadol withdrawal include:

  • Diarrhea
  • Sweating
  • Restless leg syndrome
  • Stomach ache
  • Nausea
  • Muscle ache
  • Anxiety
  • Insomnia
  • Tremor

Is Tramadol safe for pregnant and breastfeeding women?

There is no adequate research on the risks of using this drug in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. This drug is included in the risk of pregnancy category C according to the US Food and Drugs Administration (FDA).

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk,
  • B = No risk in some studies,
  • C = Maybe risky,
  • D = There is positive evidence of risk,
  • X = Contraindications,
  • N = Unknown


What medicines might interact with Tramadol

Although some drugs may not be taken together at all, in other cases some drugs can also be used together although interactions may occur.

In cases like this, the doctor may change the dose, or do other prevention things that are needed. Let your doctor know if you are taking other medicines both over the counter and from a prescription.

Use of this drug in conjunction with the drugs below is not recommended. Your doctor may decide not to give you this medicine or replace other medicines that you take.

  • Naltrexone
  • Rasagiline
  • Selegiline

Using this drug with some of the medicines below is usually not recommended, but in some cases it may be needed. If both of these drugs are prescribed to you, your doctor will usually change the dosage or determine how often you should take these drugs.

  • Acetophenazine
  • Amphetamine
  • Bromperidol
  • Buspirone
  • Carbamazepine
  • Carbinoxamine
  • Ceritinib
  • Chlorpheniramine

Taking this drug with the drugs below can increase the risk of side effects, but in some cases, the combination of these two drugs may be the best treatment.

If both of these drugs are prescribed to you, your doctor will usually change the dosage or determine how often you should take these drugs.

  • Digoxin
  • Perampanel
  • Quinidine
  • Warfarin

Can food or alcohol react with Tramadol?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can affect Tramadol's performance?

Other health conditions that you have can affect the use of this drug. Always tell your doctor if you have other health problems, especially:

  • Alcohol abuse, still or ever
  • CNS depression, still or never
  • Drug abuse, still or ever
  • Head wound
  • Hormone Problems
  • Increased pressure on the head
  • Infection in the central nervous system (central nervous system-CNS)
  • Mental disorders, still or ever
  • Phenylketone allergy, still or ever
  • Respiratory depression (hypoventilation or slow breathing)
  • Seizures or epilepsy, still or ever
  • Severe stomach problems - Use with caution. The chance of serious side effects can increase
  • Severe lung or respiratory problems (such as asthma, hypercapnia) - Medication should not be used
  • Kidney illness
  • Liver disease (including cirrhosis) - Use with caution. The effect can be increased because the process of spending drugs from the body is slower
  • Phenylketonuria (PKU) —Tablets that dissolve in the mouth contain phenylalanine, which can worsen your condition.


What should I do in an emergency or overdose?

In case of emergency or overdose, contact your local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

Symptoms of overdose include:

  • Reduced pupil size (dark circles in the middle of the eye)
  • Difficulty breathing
  • Severe drowsiness
  • Unconscious
  • Comma (loss of consciousness over a period of time)
  • Heartbeat slows down
  • Weak muscles
  • The skin is cold and moist

What should I do if I miss a dose?

If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose.


MIMS. Tramadol. 2016. http://mims.com/Indonesia/Home/GatewaySubscription/?generic=Tramadol Accessed December 12th, 2015

Reviewed Date: May 2, 2018 | Last Edited: May 2, 2018

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